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FACULTY OF health scienceS
range of kidney disease and resistant hypertension, 24
blood pressure monitoring renal biopsies, prevention
of chronic kidney, and cardiovascular risk assessment.
The unit is supported by a dedicated team of transplant
surgeons. Treatment is offered to both private and indigent
patients. It also offers out reach programmes to Khayelitsha
Community Health Centre and GF Jooste Hospital locally,
and to George Hospital, the Northern and Eastern Cape.
There is active training programme for senior registrars in
Nephrology and the unit is currently training 5 nephrology
fellows. The division supports the Department of Medicine
training of medical students, specialist physicians and
professions allied to medicine. The division also supports
training of renal technologists and the nephrology course
for nurses.
The main academic research activities of the division
relate to renal bone disease; systemic lupus erythematosis
(SLE); genetics of salt sensitive hypertension; diabetic
nephropathy; classification, genetics, prevalence and
treatment of HIV associated nephropathy; the genetics of
ACE inhibitor related angioedema in black and coloured
South Africans; treatment of renal artery stenosis due to
atherosclerosis; vascular calcification in CKD stage 5
and its effects on central aortic BP; detection of vascular
calcification; and the effects of antiviral treatment on BP in
patients living with HIV.
Divisional Statistics
Permanent and Long-term Contract Staff and
students
Associate Professors
2
Senior Lecturers
2
Emeritus Professor
1
Senior registrar
5
Part-time consultant
1
Medical officers
3
Medical registrars
3
PhD Students
0
Total
15
Research Fields and Staff
Associate Professor C.R. Swanepoel
HIV and the kidney – worked on the development of a HIV
and renal disease classification. Principal researcher is
Dr N Wearne.
Dr Z Barday
Dr Yvonne Trinder
Dr Ike Okpechi
Lupus registry; Quality of life in CAPD patients
Associate Professor Brian Rayner
Cardiovascular outcomes in renal atherosclerotic lesion
(CORAL Study): A prospective, multi-center, unblinded,
two-arm, randomized trial; Genetics of salt sensitive
hypertension (PhD dissertation); PTH and low renin
hypertension; The genetics of ACE inhibitor related
angioedema in black and coloured South Africa
Dr Craig Arendse
Prospective observational study of all HIV positive patients
who undergo a renal biopsy at GSH hospital to establish
best medical management, mortality and spectrum of
disease.
Dr Nicola Wearne
Retrospective analysis of all HIV positive renal biopsies
between 2004 and 2008 at GSH hospital; Prospective
observational study of all HIV positive patients who
undergo a renal biopsy at GSH hospital to establish best
medical management, mortality and spectrum of disease;
HIV related renal disease: Histological Classification;
Randomised controlled study: Treatment of HIV +ve
patients with confirmed HIVAN on renal biopsy with
Corticosteroids; Epidemiology of renal dysfunction and
chronic kidney disease in HIV positive HAART naïve
patients
Dr Bonginkosi Mahala
Retrospective analysis of biopsy proven focal
segmental glomerulosclerosis; MYH9 polymorphisms
and susceptibility to FSGS, HIVAN and hypertensive
nephrosclerosis; Cardiovascular outcomes in renal
atherosclerotic lesion (CORAL Study): A prospective,
multi-center, unblinded, two-arm, randomized trial;
Stella Alagbe
New Onset Diabetes in renal transplant recipients
Dr Rob Freercks
Impact of Vascular calcification on central blood pressure
in CKD-5D; Ambulatory blood pressure monitoring in CKD-
5D; Detection of vascular calcification in CKD-5D
Contact Details
Postal Address: E13 Groote Schuur Hospital, Observatory,
7925
Telephone: +27 21 404 3318
Fax: +27 21 404 5215
E-mail: mmcadi@pgwc.gov.za