Page 315 - UCT Research Report 2011

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FACULTY OF health scienceS
Registrars
Dr Didi Motsepe (supernumerary registrar)
Relevance of a positive specific latex IgE (RAST) result in
a non-medical occupational setting
Dr Fatema Esmail (supernumerary registrar)
Genetic basis for atopic eczema with special relevance to
filiggrin gene defects in African children and their patterns
of sensitization, collaborative project with University of
Dundee, Dublin and Zurich
Dr Vanessa Lapiner
Quality of life in patients with vititligo, genetic skin diseases
Dr Ilsphi Browne (5/8 supernumerary post)
Changing pattern of skin diseases in HIV-infected patients
Dr Thuraya Isaacs (5/8 supernumerary
registrar)
The clinical patterns of Kaposi/s sarcoma relative to
HHV8 clades
Dr Nomphelo Gantsho (5/8 supernumerary
post)
The epidemiology and treatment of acne keloidalis
Researchers
Dr Rannakoe Lehloenya (Discovery Health
PhD Fellow)
Drug reactions and hypersensitivity testing; Immune
reconstitution syndrome in HIV
Dr Samantha Eisman (sessional consultant)
Teledermatology and the use of cell phone technology;
Laser therapy
Dr Anita Bonthys (MRC research fellow)
A study of pigmented naevi
Dr Bianca Tod (supernumerary research
fellow)
Spectrum of skin rashes in measles and the effect of HIV
co-infection
PN Judy Wallace (Sister - Ward G23)
Nursing care of severe drug reactions; Re-challenge of TB
medication following serious cutaneous drug reactions;
Management of leg ulcers
PN Nora Christians
Lecturer for the UCT Dermatology Nurse Course;
RegiSCAR data capture; Applied research
S. Woods (IT consultant – part-time)
Development and maintenance of dermatology databases
and teaching slides
Chronic Diseases Initiative in
Africa (CDIA)
Director: Professor N.S. Levitt
Divisional Profile
The Chronic Diseases Initiative in Africa (CDIA), funded
by the United Health Chronic Disease Initiative and the
National Heart Lung Blood Institute (NHLBI),was launched
in November 2009. It forms part of an 11 centre Global
Health Initiative focussing on non communicable disease
research in the developing world. CDIA comprises of
a network of researchers drawn from the University of
Cape Town, Stellenbosch University and the University of
the Western Cape, along with the South African Medical
Research Council, Harvard University and Shree Hindu
Mandal Hospital, Tanzania, in addition to representatives
from local and national Departments of Health. CDIA’s
mission is to serve as a collaborating initiative for the
development, evaluation and dissemination of methods
and programmes to prevent chronic non-communicative
diseases, and improve the quality of care for people with
these diseases and their risk factors.
Research
Currently funded projects:
Develop, evaluate and implement integrated chronic
disease management guidelines for primary care providers
Eden District Randomised, Controlled-Trial for Primary
Care of Chronic, Non-Communicable Diseases (NCDs)
will be conducted to test the effectiveness of a novel
training approach based on a previously tested model of
syndromic screening and management of patients with
conditions such as chronic obstructive pulmonary disease,
asthma, or TB. A written guideline (101 pages) has
been prepared for the management of chronic diseases
by primary care nurses and doctors. The trial will test
whether the approach, previously shown to be effective for
respiratory diseases including tuberculosis and HIV/AIDS,
will remain effective when expanded to include the primary
care management of other major categories of chronic
diseases (hypertension, diabetes, depression).
To calibrate and validate a non-laboratory based screening
tool for cardiovascular disease (CVD) risk prediction in
South Africa
The predictive performance and risk discrimination of
the non-laboratory-based risk score to five commonly
used laboratory-based scores (Framingham CHD and
CVD, SCORE for low and high risk settings, CUORE) was
evaluated in 11 South African cohorts, which represents all
cross sectional studies conducted in the country over the
past 25 years for which the necessary data were available.